Pulmotype provides pathologists with a valuable new tool to help their oncologist clients understand which patients are eligible for a number of new therapies now available for the treatment of NSCLC . Its ability to accurately sub-classify lung cancer will enable physicians to make much more informed and effective therapy decisions.

The phosphoinositide 3-kinase (PI3K) family is a group of enzymes that generate lipid 'second messengers' that mediate signal transduction. PI3K signaling initiates normal cell processes that are frequently disrupted by carcinogenesis: growth, differentiation (the structure and/or function of a cell is changed), survival, proliferation, migration, metabolism, and metastasis.

The epidermal growth factor receptor (EGFR) is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands. EGFR exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α.

The epidermal growth factor receptor (EGFR) is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands. EGFR exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α.